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2 New Cannabinoids Identified

2 new cannabinoids discovered

2 new cannabinoids have been identified by scientists as the legalization of Cannabis sweeps around the globe. Scientific understanding of the drug appears to be asking more questions than it is answering at the moment. As the world slipped into the new decade, scientists in Italy have discovered two new previously unidentified cannabinoids in marijuana. What this means for users remains a mystery at this point, as they have no idea what effects these new cannabinoids have on the human body.

The 2 New Cannabinoids

One of them, Tetrahydrocannabiphorol (THCP) has a similar structure to the more well-known Tetrahydrocannabinol (THC). This is, of course, the main compound in marijuana, and is responsible for its psychoactive properties. The new cannabinoid, however, is reportedly 30 times more potent than THC. Pharmacological tests have shown THCP to “induce hypomotility, analgesia, catalepsy and decrease rectal temperature.” This possibly suggests that it has similar effects on the body as THC. At this stage, it is not yet clear whether THCP is psychoactive or indeed if it produces the same ‘highs’ as THC. Tests on mice though, seem to indicate that much lower doses achieve the same results.

The second cannabinoid identified is Cannabidiphorol (CBDP), which is linked to the antioxidant and anti-inflammatory CBD. This is also an anti-convulsant and acts as an  “antagonist” of THC’s negative effects. The scientists say in their report that to the best of their knowledge, a Phytocannabinoid of these structures, i.e. with a “linear alkyl side chain containing more than five carbon atoms”, has never before been reported as occurring naturally. It is hoped that this could help scientists to understand why different strains induce different effects on the human body. This hopefully will result in different feelings and may promote more health consequences. Hopefully, this is just another step towards fully understanding the positive effects of cannabis.

Scientific Report Looks Positive

An article published  on the Scientific Reports Website stated that “A number of clinical trials and a growing body of literature provide real evidence of the pharmacological potential of cannabis and cannabinoids on a wide range of disorders from sleep to anxiety, multiple sclerosis, autism, and neuropathic pain.” The authors added that they expect THCP to deliver “an even higher binding affinity for CB1 receptor [in the brain] and greater cannabimimetic activity than THC itself.” So far it’s all good news for the 2 new cannabinoids.

It is now widely accepted that Cannabis Sativa has positive health effects. Illnesses such as glaucoma and epilepsy demonstrate positive changes when the patient takes the drug. Incredibly cannabis still remains illegal in most countries and is one of the World’s most controversial and illicit drugs. However huge advances are being made. 

The 2 New Cannabinoids are Stronger but Evident in Small Quantities

This plant produces an amazing 150+ phytocannabinoids of which THC and CDB are the most well known. THC was up until now thought to be the only one that produces a high. Whilst the two new compounds were evident in only low amounts, researchers feel that other strains of weed may well carry them in higher levels. 

The authors of the Scientific Report article added, “In our opinion, this compound should be included in the list of the main Phytocannabinoids to be determined for a correct evaluation of the pharmacological effect of the cannabis extracts administered to patients. In fact, we believe that the discovery of an extremely potent THC-like Phytocannabinoid may shed light on several pharmacological effects not ascribable solely to THC.” 

Clearly there is still much work to be done, but scientists are confident that the more they discover, the more that the positive aspects of marijuana can be demonstrated. As many more countries rush to join those that have already legalized marijuana, more research will become the norm. It is a good time to be involved in what will become one of the most lucrative businesses in the World in the coming months and years. 

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Strain Reviews

5 of the Best CBD Strains of Cannabis

Best CBD Strains

Even the most newbie of all will, by now, of heard about THC and CBD in Cannabis. But what are the differences? And what is are the best CBD strains and THC strains good at. In this article, we are concentrating on CBD. The main differences are that it is Tetrahydrocannabinol (THC) is what gets you high and Cannabidiol (CBD) that has the medical properties.

THC is a phytocannabinoid that was first discovered in 1940. It is thought to be part of the plant’s self-defense system. It is involved in the fight against insect predation, ultraviolet light, and environmental stresses.

CBD is just one of 113 cannabinoids that have thus far been identified. They account for up to 40% of cannabis extract.

What are the Best CBD Strains used for?

The best CBD strains contain high levels of CBD and are now accepted by the main health organizations in the world as useful tools in the fight against many medical disorders. In 2018 The American Food and Drug Administration (FDA) approved the cannabidiol drug Epidiolex for the treatment of two types of epilepsy: Dravet syndrome and Lennox-Gastaut syndrome in children with refractory epilepsy. 

For Dravet syndrome, the use of the Charlottes Web strain was shown to have particularly good efficacy. The strain was named after Charlotte Figi who sadly passed away on April 7th, probably as a result of Covid-19, though this was not fully diagnosed. See the obituary posted on The Mary Jane Website on April 9th. 

Over the years CBD has been used to successfully treat or alleviate the symptoms of Parkinson’s Disease, anxiety disorders, stress, insomnia, acne, and heart disease. It is widely accepted now as a major help in general pain relief, in some cases people suffering conditions that cause constant pain, have been helped tremendously by taking medical marijuana. Cancer sufferers, in particular, are stating that CBD has helped in the management of their condition.

We must look at this responsibly. Medical marijuana is not a wonder drug that will be a panacea for all ills. However, it is also imperative that we look at this with an open mind, guided by the testimonies of those who are gaining valuable help by its use and the doctors who support them.

Here are 5 of the Best CBD Strains 

Electric Kush

CDB 10%

Grown By: Capital Hemp

Certificate of Analysis:  https://molinoglass.com/wp-content/uploads/2020/01/Electric-Kush-Hemp-COA.pdf

Available From: Molino Glass Bongs

best cannabis strains - electric kush
Electric Kush Photo: Molino Glass Bongs

One of the absolute best strains of CBD laden cannabis around. This Sativa-dominant hybrid is organically grown by Capital Hemp in Sacramento, California. It’s a new strain of Girl Scout Cookie. In any way, similar to Purple Cookie, though carrying more of a Cherry Pie / Durban Poison mix. Reviews so far say that it looks and tastes amazingly good. The dominant terpenes are Myrcene, β-Caryophyllene, Guaiol, and a-Humulene. It carries scents of fresh mango and spices.

ACDC

CBD: 20%

Grown by: various  

Certificate of Analysis: http://archive.analytical360.com/m/archived/192193

Available From: Best Pot Cannabis Store

best CBD strains of cannabis - ACDC
ACDC Photo: Best Pot

This is a truly unusual strain of cannabis. Whilst the CBD level regularly hits 20% the THC is one of the lowest available at just 1 to 6%. This means that it can be used to treat many ailments without any sort of psychoactive effect whatsoever.

It is an evenly balanced hybrid at 50%Indica and 50% Sativa, a cross between Cannatonic and Ruderalis. The strain has achieved great success winning several Cannabis Cup awards, making it undoubtedly one of the best CBD strains around.

It has a terrific earthy, sweet, aroma and some may taste a hint of fruit. When smoked many users say they also get cherry and lemongrass scents. The buds are tight but deceptively airy, green in color with orange hairs. It is often available in capsule, tea, tincture, and lotion form.

Many reviewers cite its ability to treat Anxiety, Tendonitis and many other painful ailments.

Charlotte’s Web

CBD: 13%

Grown by: Stanley Brothers of Colorado

Certificate of Analysis: https://www.charlottesweb.com/batch-reports

Available From: Charlotte’s Web Company

best CBD strains of cannabisd
Charlotte’s Web. Photo: Charlotte’s Web

As mentioned in the introduction this strain was created for Charlotte Figi who suffered from a rare condition known as Dravet Syndrome. This is widely acknowledged as one of the best strains of cannabis for fighting this and other disorders. Charlotte went from having 300 seizures a week to just around 2 or 3 per month. 

Charlotte’s Web was specifically cultivated from hemp for its high CBD and low THC content. Charlotte’s Web Company use these genetics to create a wide range of products. As they are hemp-derived they are not intoxicating. This was necessary, of course, as originally they were designed for a child. CNN featured the weed and the amazing effects it was having on Charlotte Figi, this increased its popularity hugely.

Cherry Wine #32 CBD Flower

CBD: 18.89%

Grown by: Old Soul Hemp Company  

Certificate of Analysis: https://molinoglass.com/wp-content/uploads/2020/02/Cherry%20Wine%20%2332.pdf

Available From: Molino Glass Bongs

best CBD Strains of Cannabis

This is a pleasant tasting Sativa dominant variety, known for its citrus scents. It has a calming and relaxing influence and is said to produce a very slight hight, though nothing to worry about if that is an issue. It is grown in Nevada by Old Soul Hemp Company. Reviews are extremely positive with many users claiming that it has helped asthma and anxiety issues and particularly pain relief for athletes suffering strains, aching muscles and even injuries like torn ACLs. Users unanimously list feeling happy and relaxed when using it.

Cannatonic

CBD: Up to 17%

Grown by: various

Certificate of Analysis: 

Available From: Weed Seeds Express

Cannatonic. Photo- Maximum Yield

Cannatonic is the perfect strain for CBD fans. It rose in popularity quite quickly due to its high CBD content and low THC content. It has a wonderfully sweet and citrus aroma, with woody notes. The plant is quite easy to grow, provided you watch out for fungal infections. 

Indoor growth promotes higher yields making it ideal for home growing. It can, however, be grown outdoors as well. Cannatonic has received wonderful reviews from people suffering from various types of pain. Conditions like migraine or fibromyalgia seem especially responsive to this strain. 

It has been often described as having calming and uplifting effects. For these reasons, it is strongly recommended for the treatment of sleep issues, anxiety and depression. It is also dispensed for the treatment of epilepsy, OCD, OCS, and schizophrenia.

Summary

We hope that our best CBD strains list acts as a great starting off point for you on your journey with CBD cannabis. For whatever reason you are using it, we feel that these strains are particularly good and are laden with the best qualities of medical marijuana. 

Although these all have extremely low concentrations of THC Mary Jane’s Garage makes no guarantees that any individual will be able to pass drug tests after using these products.

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News

Stay Safe With Deliveries During Covid-19 Pandemic

Covid-19 sterilizing

During the Covid-19 pandemic, it is imperative that we all change our lifestyles and adapt literally everything that we do in order two stay safe and more importantly keep our elderly loved ones safe. Social distancing and self-isolation are the very least that we can do. It’s boring and frustrating but it should only be for a relatively short space of time. We can do this.

Luckily for a lot of us, we can still get our favorite cannabis products sent to us at this time. If you are lucky enough to have a dispensary near you that is doing deliveries, take advantage of that service. You are much safer staying in and letting your stash come to you than you are going out searching for it.

Covid-19: Parcel Delivery Guide

Of course, having parcels arrive at your door still carries a slight chance of transferring the virus via the package to your house. This does not, however, mean that you should panic. Whilst the risk is slight it is still there. Fortunately, the solutions to this issue are extremely easy.

It has been estimated that the Covid-19 virus stays active on different substances for different lengths of time. For example, on cardboard, it would seem to live for up to 24 hours, on steel or plastic for possibly three days and copper just four hours.

Therefore if you have a garage or a utility room in your house get the delivery guy to drop it directly in there, shut the door and just leave it for about 4 days. A virus cannot jump from one surface to another. If the package is left untouched for four days all traces of any viruses on or inside the box will be long gone by the time you open it.

Even if you have to bring it inside your house, simply put it in a position where it will not be disturbed, leave it then immediately wash your hands thoroughly for at least twenty seconds. You will then be free of all traces of Covid-19.

If You Cannot Store Packages

This is still not a problem provided you adhere to certain protocols. Bring the package into an open space in your house. Let’s say the kitchen. Before doing so, sterilize a working space using a proprietary bleach or a good quality sanitizer. The American Environmental Protection Agency (EPA) has issued a list of no less than 370 products, which are officially approved for use against Covid-19.

Don’t worry if you cannot get hold of these products. Good household bleach is sufficient. Mix four to six teaspoons of bleach with a quart of water and put it in a spray bottle. This is perfectly adequate. Never use neat bleach or course, this is dangerous.

Another product is rubbing alcohol. This needs to be at least 70% isopropyl, and the strongest the better. Please Note: Some spurious websites are recommending using alcoholic drinks like Vodka or Whisky. This is nonsense. First of all, it will not work, secondly, these products have much better use and thirdly look at the cost!

Remember it is only work surfaces and packaging that you need to sterilize. Place your package on the pre-sterilized work surface. Spray the entire outside of the box before opening. Then spray each internal package as you lift then out. Dispose of the outer packaging. All your goodies are now ready for use. There is no need to sterilize the actual products themselves. Nobody wants to taste bleach with their weed and you don’t want to be lighting something that is soaked in 90% alcohol.

Immediately after unpacking your products wash your hands thoroughly with soap and warm water for at least twenty seconds.

Summary

Follow these simple instructions and you will be keeping you and your family safe. Always remember never to mix any cleaning or sterilizing products. Chemicals when mix can cause all kinds of problems.


Stay Safe, Stay Well and remember, Stay Home

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Featured

2020 report, Bees Love Cannabis, What’s Not to Like?

bees love cannabis

To discover to what extent bees love cannabis, two reports have been published in 2019. First, a report was published in March 2019 by Colorado State University This was followed by another in December 2019 by Cornell University in Environmental Entomology.  Both studies looked at the devastating effect the planet is having on the bee population and the way in which legal cannabis production could have a positive impact. 

The findings were quite surprising. For example, the latest one found that the tallest weed plants attract an amazing 17 times more bees than the shortest.  

Bees Love Cannabis

Bees are cool, Cannabis is cool, bees love cannabis, how great is that? The study explains that the new, rapidly expanding hemp product Cannabis sativa (Cannabaceae), is exclusively wind-pollinated. Although it produces no nectar, it produces large amounts of pollen,  which attract bees in large numbers. The study collected bees from the crops in New York and identified 16 different species. Plant height not only brought more bees but more varieties as well. It is determined that hemp “has the potential to provide a critical nutritional resource to a diverse community of bees during a period of floral scarcity”. Good news for the bees and good news for us.

Growers Should See Bees as their Friends

Hemp production is increasing rapidly since legalization. All those with a stake in this business should work towards supporting bee communities and look at the positive impact they have on crops before developing pest management strategies. 

Bees provide an essential service through pollination. In recent years their decline has been well documented. This is due mainly to the loss of habitat and the increased use of pesticides. Large scale intensive agriculture has had a devastating effect on bee populations with some species becoming extinct in different parts of the world. 

Climate change is another factor and a report published in ScienceMag in February 2020 points out that “Climate change could increase species’ extinction risk as temperatures and precipitation begin to exceed their historically observed tolerances.”

It is imperative that we all work together regarding both farming methods and land management practices. These threaten the sustainability of the bees’ natural pollination services upon which our agricultural systems rely. The importance of bees cannot be over-emphasized. Without them, we will lose many of the crops that we take for granted today. 

Species and Numbers of Bees Collected

A total of 335 bees from 17 species were collected from 11 sites during the sampling period.  See Table below: 

bees love cannabis

Cross-Pollination from Hemp will not Enter the Food Chain

Although bees love cannabis and will spread the pollen to other plants,  have no fear. The new study looks at the effect that bees enjoying their daily intake of cannabis rich pollen will have on other crops in the food chain. They state that  “The rapid expansion of hemp production in the United States… may have significant implications for agroecosystem-wide pollination dynamics.” However this will not turn the population into potheads as “cannabinoid-rich pollen won’t infiltrate our diets, nor will it have an impact on bee development due to the loss of cannabinoid receptors in insects.”

Hemp is a late-season crop. It flowers at a time when others are creating a seasonal floral dearth. It is therefore said that hemp will “fill in the gaps” at exactly the times when it is needed.

Summary

As hemp produces high yields of pollen at a time when other crops do not, it was found that this supports the bee communities. The effectiveness of hemp in supporting bee communities is influenced by the composition of the landscape; the height of the crops produced; and temporal factors. It is suggested that growers should consider the risks to bees when developing pest management practices. 

Hemp is a late-season crop flowering crop during a period of seasonal floral dearth. It, therefore, may be a strong candidate to enhance pollinator populations. Bees love cannabis and this is good news for all crops, not just hemp.

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